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专利名称:Administration of macrophage targeted
formulations of compounds which modulatecholesterol-metabolizing enzymes fortreatment of atherosclerosis
发明人:Perry M. Kim,Robert Bender申请号:US11399066申请日:20060406
公开号:US20060257466A1公开日:20061116
摘要:Macrophage targeting formulations of compounds for treating atherosclerosis,in particular compounds which modulate cholesterol-metabolizing enzymes including,but not limited to acyl CoA:cholesterol acyl transferase (ACAT) inhibitors, cholesterolester hydrolase (CEH) enhancers and combinations thereof, are provided. Methods forshort term administration of these macrophage targeting formulations to promoteregression and/or inhibit formation of atherosclerotic plaque, as well as to treat
atherosclerosis, inflammation, coronary heart disease and cardiovascular disease are alsoprovided.
申请人:Perry M. Kim,Robert Bender
地址:Inverary CA,Ottawa CA
国籍:CA,CA
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