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专利名称:Process for producing derivatives of
hydroxy-methylene diphosphonic acid
发明人:LEROUX, YVES申请号:EP83401701.4申请日:19830824公开号:EP0104974B1公开日:19870311
摘要:New process for the production of derivatives of hydroxy-methylenediphosphonic acid from the corresponding carboxylic acid comprising: a) mixing saidcorresponding carboxylic acid with a P III reactant selected from the group comprised ofphosphorus tri-halides, phosphorous acid and mixtures thereof, the reaction mixturebeing protected from moisture; characterized in that the molecular ratio between the PIII reactant and said corresponding carboxylic acid is comprised between 13/12 and 18/12and in that it further comprises the step: b) heating said reaction mixture to atemperature comprised between 80 and 110C during a period of time comprisedbetween 3 and 20 hours approximately.
申请人:MINEMET RECHERCHE
地址:1, avenue Albert Einstein B.P. 106 F-78191 Trappes Cédex FR
国籍:FR
代理机构:Ricalens, François (FR)
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